In October 2023, the Sinaloa Cartel looked to publicly signal that it was moving away from fentanyl trafficking amid an intensifying crackdown on its operations by U.S. and Mexican authorities. As one of two major suppliers, this would be a significant shift, but it remains unclear how genuine or effective Sinaloa’s transition will be. Two organizations, the Sinaloa Cartel, and the Jalisco New Generation Cartel, manage most of the production and distribution networks, often depending on American citizens to smuggle fentanyl across the border.
Fentanyl can also be “diverted.” That’s when the drug is prescribed by a doctor but isn’t used as directed or is sold or given to someone else. The Oregon Health Authority presents this information with the acknowledgement that this data represents individuals whose loss of life has had an enormous impact on their families and communities. Using too much of this medicine may cause reduced infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children. Call you doctor right away if you have blistering, lesions, a rash, redness, or swelling of the skin, especially at the site of application.
Side Effects
A fentanyl overdose can occur after the drug is injected, swallowed, snorted, or smoked. Symptoms of a fentanyl overdose, including slow or absent breathing, generally occur within minutes of the overdose. Death can follow quickly if the overdosed person isn’t treated. For people who are addicted to fentanyl, there are safe and effective treatments available. Scientists are also working on opioid vaccines that would cause a person to develop antibodies to particular opioids and block their effects. This would offer a new approach to treating substance abuse, but the results of this research will likely not be known for years to come.

Be aware that it may take more than one dose of naloxone to reverse an opioid overdose. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems. Your doctor will tell you how much of this medicine to use and how often.
Products & Services
Lofexidine, a central α2-adrenergic receptor agonist, was the first non-opioid medication that was approved by the United States FDA for the treatment of opioid withdrawal103,104. Lofexidine has fewer prescriptive barriers and comparable efficacy and safety relative to other opioid receptor agonizts, but it is generally more expensive. Sparse data are available on the effectiveness of interventions to prevent overdoses that are caused by illicitly manufactured fentanyl (Table 1).
If you are prescribed an opioid medication to treat pain, you can ask for a co-prescription of naloxone. Xylazine is a powerful non-opioid sedative used in veterinary medicine. Xylazine is not approeved or safe for human use in any amounts. When fentanyl or other opioids are mixd with xylazine, the effects on breathing can be life-threatening. Xylazine use can lead to unresponsiveness, forgetfulness or memory loss, dangerously low blood pressure, slowed heart rate, and reduced breathing.
According to the report, most of this fentanyl originates in China. China has cracked down on fentanyl and some of its subtypes, or analogues, but the online dealers often tweak the formulas of their drugs slightly to stay ahead of bans. For example, when China announced it would ban one fentanyl product, called U-47700, on July 1, one fentanyl dealer advertised a “hot sale” of the product through June. “All must go till 1 of July,” the “special offer” read, according to the report. Facing the reality of a loved one’s fentanyl addiction is an emotional challenge.

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This can depend on its supplier, where it is made, and what drugs it is comprised of. The cost of fentanyl will depend on the type of fentanyl the individual chooses to purchase. The fentanyl patch street value can be closer to $40 and lasts up to 72 hours. For many, patches can be an effective and affordable way to get fentanyl.
What Does It Mean To Have A Substance Abuse Problem?
For a comprehensive and focused approach, inpatient facilities provide an immersive healing environment. These facilities offer a structured and closely monitored setting where individuals can commit fully to their recovery. Guided by medical professionals and an array of therapeutic modalities, inpatient programs equip you with the necessary tools to break free from the grip of addiction. Aiding someone battling drug addiction requires striking a balance between supportive gestures and enabling behavior. Establishing healthy boundaries might involve refusing financial aid that supports their habit or not allowing substance misuse within your home environment.
- Illegal fentanyl supplies are largely produced in China and Mexico and then smuggled into the United States.
- In 2022, the US Drug Enforcement Agency seized brightly colored fentanyl pills and powder (“rainbow fentanyl”), demonstrating that fentanyl can come in various colors and formulations.
- Illegal fentanyl, however, has an unknown amount of fentanyl and may be mixed with other drugs, which may result in harmful behaviors.
- First responders will likely administer naloxone if you haven’t already, or give it to them again.
- For continuous delivery, a transdermal patch can slowly deliver fentanyl through the skin and into the bloodstream for up to 72 hours.
Which Darknet Market Is Safe
- Make sure you store the medicine in a safe and secure place to prevent others from getting it.
- Our blockchain analytics engine Nexus can be used to trace the on-chain activities of these dealers – including money laundering or dark web activity.
- Our staff can deliver care on the spot to those who use the Tacoma Needle Exchange van in our parking lot.
- Other side effects not listed may also occur in some patients.
- Some of its side effects are also caused by actions in the CNS.
This effect may last for a few days after you stop using this medicine. Check with your medical doctor or dentist before taking any of the above while you or your child are receiving this medicine. The drug fueling America’s unprecedented overdose crisis is available to mail-order directly from China by logging online. Fentanyl, a synthetic opioid that’s 50 times more powerful than heroin, can be found using a simple internet search. Because fentanyl is so potent and commonly found in the drug supply, it is easy for people to accidentally overdose on fentanyl.
NIH-funded Intervention Did Not Impact Opioid-related Overdose Death Rates Over Evaluation Period
Discarded fentanyl patches may still contain significant amounts of the drug. This can result in misuse if someone removes the gel contents from discarded patches. There are a variety of risks that accompany the use of street fentanyl. Firstly, because it has been created illegally – without any oversight or regulation – there is virtually no way to ascertain the purity of the fentanyl. It may have been contaminated with any number of dangerous pollutants and impurities during the manufacturing process. There may be other fentanyl street names based on the substance it is mixed with.


Some WA State syringe services programs can provide fentanyl test strips. The emergency and referral resources listed above are available to individuals located in the United States and are not operated by the National Institute on Drug Abuse (NIDA). NIDA is a biomedical research organization and does not provide personalized medical advice, treatment, counseling, or legal consultation. Information provided by NIDA is not a substitute for professional medical care or legal consultation. Moreover, the conjugate vaccine stimulated the endogenous generation of antibodies with high affinity for a variety of fentanyl analogs140, and was shown to blunt fentanyl reinforcement142.
Many of the opioid pills and powders sold on the street are fake. They often contain fentanyl in potentially deadly amounts but are mislabeled as other opioids. The DEA sampled tablets seized nationwide between January and March 2019. It found 27 percent contained potentially lethal doses of fentanyl. Fentanyl is not only much stronger than other opioids, but it’s often added to illicit drugs without people knowing.
If A Person Has Naloxone, Is Fentanyl Safe To Use?
Its potency means you might think you’re getting a bargain, as a little goes a long way. But this financial perception masks a harsh reality — its strength makes accurate dosing a gamble. In a study about fentanyl sales on the dark web, a gram of non-pharmaceutical fentanyl was priced at an average of $1,470 for listings offering less than 5 grams.

Building on this foundation, the project’s second phase provides timely analysis of the shifting policy and crime market landscape while continuing to offer policy recommendations. First responders will likely administer naloxone if you haven’t already, or give it to them again. Naloxone only works in the body for 30 to 90 minutes, so it’s possible for someone to still have overdose effects after the medication wears off or needs multiple doses. Sometimes people freeze fentanyl patches and cut them into smaller portions. Then they put these small pieces in their cheeks or under their tongue. This overdose rate has continued to rise in part because fentanyl is often mixed into or sold as other drugs.
Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Help educate your loved one on the risks of fentanyl and make sure they know these harm reduction strategies. Fentanyl is a medicine that can harm or cause death to a child. Patients and caregivers should keep this medicine out of the reach of children. Carefully dispose of any partially used units or unused medicine properly. Ask your healthcare professional how you should dispose of any medicine you do not use.